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Top 10 Ulcerative Colitis Medications — Relieve Heartburn

Ulcerative Colitis medications are those which are used for treatment of inflammatory bowel disease (IBD) that causes long lasting inflammation and ulcers (sores) in your digestive tract. While Heartburn is associated with increased HCL secretion that backs up into oesophagus. It causes burning and painful feelings in chest and throat.

Ulcerative Colitis Treatment

The basis of Top 10 Ulcerative Colitis medications is, How much effective medicine is and the duration of relief by using these medicine.

So here we have Top 10 Ulcerative Colitis Medications — Relieve Heartburn:


Number 10 — Ulcerative Colitis Medications
— Simethicone + Aluminium Hydroxide + Magnesium Hydroxide

This is an antacid and mostly available in different combination such a as Polycrole, Acifix, Algicon, Digex MP, Trisil etc.

Reason at number 10, among Top 10 Ulcerative Colitis Medications, is because of its effect of just neutralising acid produced in stomach.

These agents are ant-acids; means reduces the acid action because of their basic nature. Their function is just to neutralize the acid not stopping the production of acid.

Indications:

If you are suffering from Flatulence, Bloating, IBS (Irritable Bowel Syndrome), Peptic Ulcer, Esophagitis you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 1-2 tea spoons after meal and at bed time or as recommended by Doctor or Pharmacist.
Children: 0-1 tea spoons after meal and at bed time or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to any component of product.

Side Effects:

It may cause Diarrhea, Constipation, Itching, Burning and rashes.


Number 9 — Ulcerative Colitis Medications
— Alginate + Calcium Carbonate + Sodium Bicarbonate

Reason at number 9, among Top 10 Ulcerative Colitis Medications, is because of its effect of just neutralising acid produced in stomach.

This is an antacid and mostly available in different combination in different countries, such a as Gaviscone, Gaviscon Advance, Acidex, etc.

Indications:

These agents are used as adjunctive therapy as an alternative drug of choice in GERD (Gastro-esophageal Reflux Disease). It is also used in Dyspepsia.

Dose:

Adult: 2-4 tea spoons after meal and at bed time or as recommended by Doctor or Pharmacist.
Children: 0-1 tea spoons after meal and at bed time or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to any component of product.

Side Effects:

It may cause Urticaria, Anaphylaxis and Bronchospasm.


“If overdose of any Antacids occurs, it will cause rapid alkali-nation of Stomach subsequently an increased production of acid (HCl) to balance the gastric pH. That leads to further complication of acidity and different forms of ulcers including mouth ulcer, stomach ulcer, duodenal ulcer.” Dilshad Zaman – Pharmacist


Number 8 — Ulcerative Colitis Medications
— Rabeprazole

Reason at number 8, among Top 10 Ulcerative Colitis Medications, is because of its inhibition of Proton Pumps and reduction in acid production.

Some of brand names of rabeprazole are Rabeprazole Sandoz, Sivem, Aciphex, Bepra, Eraze, Rabosh etc.

Rabeprazole is proton pump inhibitor and used as an anti ulcerative agent. Proton pumps are found on secretary surface of gastric parietal cells. As a result secretion of hydrogen ions into gastric lumen is restricted. It inhibits basal and stimulus-induced acid secretion.

Indications:

If you are suffering from Zollinger Ellison Syndrome, Gastric and Duodenal Ulcer, Gastroesophargeal Reflux Disease, Helicobacter Pylori associated Ulcer you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 20-60mg PO 24 hourly before meal or as recommended by Doctor or Pharmacist.
Children: For >12 years 20mg 24 hourly before meal or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to Rabeprazole or any proton pump inhibitor.

Side Effects:

It may cause Headache, Pharyngistis, Abdominal Pain, Constipation, Diarrhea, Rashes and Pruritis.


Number 7 — Ulcerative Colitis Medications
— Famotidine

Reason at number 7, among Top 10 Ulcerative Colitis Medications, is because of its blocking H2 receptors and reduction in acid production.

Some of brand names of Famotidine are Femotidine Medica, Femotidine 10%, Famotidine OD, Pepcid, Peptoloc, Nocid, Famot etc.

Famotidine is a histamine H2 receptor blocker and inhibits secretion of gastric acid produced by histamine.

Indications:

Famotidine is used for the treatment of duodenal and peptic ulcers, zollinger-ellison syndrome (hyper secretion of HCl) to treat gastro esophageal reflux disorder (heartburn). You may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 20-40mg PO 24 hourly at bedtime or as recommended by Doctor or Pharmacist.
Children: 0.25mg/kg IV 12 hourly, or 0.5mg/kg PO at bedtime or as recommended by Doctor or Pharmacist. Dose should not be exceeded 40mg/day.

Contraindication:

It is contraindicated in hypersensitivity to any component of product.

Side Effects:

It may cause Headache, Diarrhea, Dizziness, Constipation, Bradycardia and Jaundice.


Number 6 — Ulcerative Colitis Medications
— Pantoprazole

Reason at number 6, among Top 10 Ulcerative Colitis Medications, is because of its inhibition of Proton Pumps and comparatively greater reduction in acid production.

Some of brand names of Pantoprazole are Normon, Mepha, Mylan, Protonix, Panzium, Protium, Zopent etc.

Pantoprazole is proton pump inhibitor and used as an anti ulcerative agent. Proton pumps are found on secretary surface of gastric parietal cells. As a result secretion of hydrogen ions into gastric lumen is restricted. It inhibits basal and stimulus-induced acid secretion.

Indications:

If you are suffering from Zollinger Ellison Syndrome, Gastroesophargeal Reflux Disease, Gastric and Duodenal Ulcer you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 20-40mg PO 24 hourly before meal or as recommended by Doctor or Pharmacist.
Children: For >5 years 20-40mg 24 hourly before meal or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to Pantoprazole or any proton pump inhibitor.

Side Effects:

It may cause Headache, Abdominal Pain, Constipation, Diarrhea, Rashes, Pruritis and Chest Pain.


Number 5 — Ulcerative Colitis Medications
— Lansoprazole

Reason at number 5, among Top 10 Ulcerative Colitis Medications, is because of its inhibition of Proton Pumps and comparatively greater reduction in acid production.

Some of brand names of Lansoprazole are Teva, Ranbaxy, Prevacid, Inhibitol etc.

Lansoprazole is proton pump inhibitor and used as an anti ulcerative agent. Proton pumps are found on secretary surface of gastric parietal cells. As a result secretion of hydrogen ions into gastric lumen is restricted. It inhibits basal and stimulus-induced acid secretion.

Indications:

If you are suffering from Heart Burn, Gastric Ulcer, Duodenal Ulcer, Risk of Ulcer associated with use of NSAIDs, Erosive Esophagitis, Gastroesophargeal Reflux Disease, Zollinger Ellison Syndrome, and Helicobacter Pylori associated Ulcer you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adults: 15-60mg PO 24 hourly before meal or as recommended by Doctor or Pharmacist.
Children: For 1-12 years 15mg-30mg 24 hourly before meal or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to Lansoprazole or any proton pump inhibitor.

Side Effects:

It may cause Headache, Diarrhea, Nausea, Constipation and Abdominal Pain.


“Wrong perception about milk that it neutralises stomach acid. The fact is, milk itself is slightly acidic that is having pH of 6.5 to 6.7. Furthermore bedtime milk may cause acidity when taken frequently.” Dilshad Zaman – Pharmacist


Number 4 — Ulcerative Colitis Medications
— Cimetidine

Reason at number 4, among Top 10 Ulcerative Colitis Medications, is because of its blocking H2 receptors and greater reduction in acid production.

Some of brand names of Cimetidine are Ciemetidine Sandoz, Cimetidine 40%, Cimetidine 20%, Tagamet, Cimet etc.

Cimetidine is histamine 2 (H2) receptor antagonist; means it blocks histamine 2 receptors. Histamine 2 receptors are mostly found in gastric area and responsible for acid secretion. When these receptors are blocked they are unable to produce acid.

Indications:

Cimetidine can be used in dyspepsia, gastric and or duodenal ulceration, and heartburn.

Dose:

Adult: 400mg PO 12 hourly before meal or as recommended by Doctor or Pharmacist.
Children: 20-40mg/kg/day IV, PO in divided doses 6 hourly or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to any component of product.

Side Effects:

It may cause Headache, Dizziness, Somnolence, Gynecomastia, Aplastic anemia and Agranulocytosis.


Number 3 — Ulcerative Colitis Medications
— Ranitidine

Reason at number 3, among Top 10 Ulcerative Colitis Medications, is because of its blocking H2 receptors and greater reduction in acid production as compared with Cimetidine and Famotidine.

Some of brand names of Ranitidine are Zantiva, Accord, Zantac, Nulcer, Anzol etc.

Ranitidine is histamine 2 (H2) receptor antagonist; means it blocks histamine 2 receptors. Histamine 2 receptors are mostly found in gastric area and responsible for acid secretion. When these receptors are blocked they are unable to produce acid.

Indications:

If you are suffering from Gastro esophageal Reflux Disease, Benign Gastric Ulcer, Hypersecretory Conditions, Erosive Esophagitis you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 150mg PO 12 hourly before meal or as recommended by Doctor or Pharmacist.
Children: 2-4mg/kg/day PO in divided doses 6 hourly or as recommended by Doctor or Pharmacist. Dose should not exceed 50mg/dose or 200mg/day.

Contraindication:

It is contraindicated in hypersensitivity to any component of product and in Pregnancy, Porphyria and inflammatory diseases.

Side Effects:

It may cause Headache, Abdominal Pain, Agitation, Alopecia, Confusion and Hypersensitivity Reactions.


Number 2 — Ulcerative Colitis Medications
— Omeprazole

Reason at number 2, among Top 10 Ulcerative Colitis Medications, is because of its inhibition of Proton Pumps and comparatively greater reduction in acid production as compared with Lansoprazole, Pantoprazole, and Rabeprazole.

Some of brand names of Omeprazole are Kitome, Prilosec, Risek etc.

Omeprazole is proton pump inhibitor and most widely used anti ulcerative agent. Proton pumps are found on secretary surface of gastric parietal cells. As a result secretion of hydrogen ions into gastric lumen is restricted. It inhibits basal and stimulus-induced acid secretion.

This medicine is OTC (Over the counter), so can be purchased without prescription.

Indications:

If you are suffering from Gastric Ulcer, Duodenal Ulcer, GERD (Gastro Esophageal Reflux Disease), Helicobacter Pylori Infection, Erosive Esophagitis, hyper secretary condition (Zollinger-Ellison Syndrome) you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 20-40mg PO 24 hourly before meal or as recommended by Doctor or Pharmacist.
Children: 2.5mg-20mg 24 hourly before meal or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to Omeprazole or any proton pump inhibitor.

Side Effects:

It may cause Headache, Abdominal Pain, Diarrhea, Nausea, Vomiting, Flatulence, Dizziness, Constipation, Rashes, Cough.


Number 1 — Ulcerative Colitis Medications
— Esomeprazole

Reason at number 1, among Top 10 Ulcerative Colitis Medications, is because of its inhibition of Proton Pumps and comparatively greater reduction in acid production.

Some of brand names of Esomeprazole are Nexium, Nexium 24HR, Nexium IV etc.

Esomeprazole is newer proton pump inhibitor and widely used anti ulcerative agent. Proton pumps are found on secretary surface of gastric parietal cells. As a result secretion of hydrogen ions into gastric lumen is restricted. It inhibits basal and stimulus-induced acid secretion.

Indications:

If you are suffering from Hyper secretary condition (Zollinger-Ellison Syndrome), GERD (Gastro Esophageal Reflux Disease), Helicobacter Pylori Infection, Risk of Ulcer associated with use of NSAIDs, Gastric or Duodenal Ulcer due to endoscopy you may take this medicine as per your doctor’s or pharmacist’s advice.

Dose:

Adult: 20-40mg PO 24 hourly before meal or as recommended by Doctor or Pharmacist.
Children: For 1-12 years 10mg-20mg 24 hourly before meal or as recommended by Doctor or Pharmacist.

Contraindication:

It is contraindicated in hypersensitivity to Esomeprazole or any proton pump inhibitor.

Side Effects:

It may cause Headache, Flatulence, Indigestion, Nausea, Abdominal Pain, Diarrhea, Constipation, Dizziness, Somnolence, Pruritis, Malaise and Blurred Vision.


Note: Other Brands of above active ingredients are also available in market. You can search from here. The purpose of describing Brand Name is just to aware of general public with OTC medicine, not promotion of above brands.


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Dilshad Zaman

Doctor of Pharmacy and Master in Business Administration. He loves to write articles on various topics.

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6 Comments

  1. This is a helpful article. I certainly can enrich my knowledge, by studying this.
    Your idea is really outstanding. Thank’s to share us such an important thing.

    Best regards,
    Balle Duke

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